28. Cao, Z.; # Sun, W.; # Zhang, J.; Zhuo, J.; Yang, S.; Song, X.; Ma, Y.; Lu, P.; Han, T.; Li, C. “Total Syntheses of (–)-Macrocalyxoformins A and B and (–)-Ludongnin C” Nat. Comm. 2024, 15, 6052.
![](http://lichaolab.com/wp-content/uploads/2024/07/TotalSynthesesMacrocalyxoformins-1024x485.jpg)
27. Li, L.;# Li, Z.;# Sun, W.; Li, C. “A Convergent Paired Electrochemical Strategy for Decarboxylative C(sp2)–C(sp3) Bond Formation” Org. Chem. Front. 2024, 11, 1941–1948.(Contributed to Organic Chemistry Frontiers Emerging Investigator Series)
![](http://lichaolab.com/wp-content/uploads/2024/07/AConvergentPaired-1024x437.png)
26. Ying, X.; Li, Y.; Li, L.; Li, C. “Nickel-Catalyzed C–I-Selective C(sp2)–C(sp3) Cross-Electrophile Coupling of Bromo(iodo)arenes with Alkyl Bromides” Angew. Chem. Int. Ed. 2023, 62, e202304177
![](http://lichaolab.com/wp-content/uploads/2023/05/TOC-1-1024x680.jpg)
25. Zhuo, J.; Zhu, C.; Wu, J.; Li, Z.; Li, C. “Reductive Radical Annulation Strategy toward Bicyclo[3.2.1]octanes: Synthesis of ent-Kaurane and Beyerane Diterpenoids” J. Am. Chem. Soc. 2022,144, 99-105.
![](http://lichaolab.com/wp-content/uploads/2021/12/Reductive-Radical--1024x556.jpg)
24. Li, Y.; Wang, Z.; Li, L.; Tian, X.; Shao, F.; Li, C. “Chemoselective and Diastereoselective Synthesis of C-Aryl-Nucleoside Analogues by Nickel-Catalyzed Cross-Coupling of Furanosyl Acetates with Aryl Iodides” Angew. Chem. Int. Ed. 2022, 61, e202110391.
![](http://lichaolab.com/wp-content/uploads/2021/10/Chemoselective-and-Diastereoselective-1024x412.png)
23. Yang, S.;# Chen, C.;# Chen, J.#; Li, C. “Total Synthesis of the Potent and Broad-Spectrum Antibiotics Amycolamicin and Kibdelomycin” J. Am. Chem. Soc. 2021, 143, 21258–21263.
![](http://lichaolab.com/wp-content/uploads/2021/12/微信图片_20211209125357-1024x470.jpg)
22. Zhang, Y.; Sun, W.; Li, C. “Nickel-Catalyzed Paired Electrochemical Cross-Coupling of Aryl Halides with Nucleophiles” Synthesis, 2022, 54, 281-294.(invited review)
![](http://lichaolab.com/wp-content/uploads/2021/10/Nickel-Catalyzed-Paired-1024x600.png)
21. Li, Z.; Sun, W.; Wang, X.; Li, L; Zhang, Y.; Li, C. “Electrochemically Enabled, Nickel-Catalyzed Dehydroxylative Cross-Coupling of Alcohols with Aryl Halides” J. Am. Chem. Soc. 2021, 143, 3536-3543.
![](http://lichaolab.com/wp-content/uploads/2021/02/图片1-1024x426.png)
20. Xu, G.;# Wu, J.;# Li, L.; Lu, Y.; Li, C. “Total Synthesis of (-)-Daphnezomines A and B” J. Am. Chem. Soc. 2020, 142, 15240–15245.
![](http://lichaolab.com/wp-content/uploads/2020/08/amchemsoc-1024x365.png)
19. Zhuo, J.;# Zhang, Y.; # Li, Z.; Li, C. “Nickel-Catalyzed Direct Acylation of Aryl and Alkyl Bromides with Acylimidazoles” ACS Catal. 2020, 10, 3895-3903.
![](http://lichaolab.com/wp-content/uploads/2020/03/ACS-Catal.-2020-2-1024x655.png)
18. Zhang, J.;# Li, Z.;# Zhuo, J.; Cui, Y.; Han, T.; Li, C. “Tandem Decarboxylative Cyclization/Alkenylation Strategy for Total Syntheses of (+)-Longirabdiol, (-)-Longirabdolactone, and (-)-Effusin” J. Am. Chem. Soc. 2019, 141, 8372-8380.
![](http://lichaolab.com/wp-content/uploads/2019/05/pub18-1024x418.png)
Supervised work
17.Takahira, Y.; Chen, M.; Kawamata, Y.; Mykhailiuk, P.; Nakamura, H. Peters, B. K.; Reisberg, S. H.; Li, C.; Chen, L.; Hoshikawa, T.; Shibuguchi, T.; Baran, P. S. Electrochemical C(sp3)-H Fluorination.
Synlett. 2019, 30, 1178.
16.Kawamata, Y.; Vantourout, J. C.; Hickey, D. P.; Bai, P.; Chen, L.; Hou, Q.; Qiao, W.; Barman, K.; Edwards, M. A.; Garrido-Castro, A. F.; deGruyter, J. N.; Nakamura, H.; Knouse, K.; Qin, C.; Clay, K. J.; Bao, D.; Li, C.; Starr, J. T.; Garcia-Irizarry, C.; Sach, N.; White, H. S.; Neurock, M.; Minteer, S. D.; Baran, P. S. Electrochemically Driven, Ni-Catalyzed Aryl Amination: Scope, Mechanism, and Applications.
J. Am. Chem. Soc. 2019, 141, 6392.
15. Li, C.#; Kawamata, Y.#; Nakamura, H.; Vantourout, J. C.; Liu, Z.; Hou, Q.; Bao, D.; Star, J. T.; Chen, J.; Yan, M.; Baran, P. S.* “Electrochemically Enabled, Ni-Catalyzed Amination”
Angew. Chem. Int. Ed. 2017, 56, 13088.
14. Li, C.#; Wang, J.#; Barton, L. M.; Yu, S.; Tian, M.; Peters, D. S.; Kumar, M.; Yu, A. W.; Johnson, K. A.; Chatterjee, A. K.; Yan, M.; Baran, P. S.* “Decarboxylative Borylation”
Science, 2017, eaam7355. (Article).
13. Qin, T.#; Cornella, J.#; Li, C.#; Malins, L. R.; Edwards, J. T.; Kawamura, S.; Maxwell, B. D.;Eastgate, M. D.; Baran, P. S.* “A General Alkyl-Alkyl Cross-Coupling Enabled by Redox-Active Esters and Alkylzinc Reagents”
Science, 2016, 352, 801-805.
(Highlighted in Angew. Chem. Int. Ed. 2016, 55, 11340; Synfacts 2016, 12, 0723)
12. Li, C.; Jones, A. X.; Lei, X.* “Synthesis and mode of action of oligomeric sesquiterpene lactones”
Nat. Prod. Rep. 2016, 33, 602-611.
11. Li, D.#; Li, C.#; Li, L.; Chen, S.; Wang, L.; Li, Q.; Wang, X.; Lei, X.*; Shen, Z.* “Natural Product Kongensin A is a Non-Canonical HSP90 Inhibitor that Blocks RIP3-dependent Necroptosis”
Cell Chemical Biology, 2016, 23, 257-266. (Featured Article)
10. Hong, B.#; Li, C.#; Wang, Z.; Chen, J.; Li, H.*; Lei, X.* “Enantioselective Total Synthesis of (−)-Incarviatone A”
J. Am. Chem. Soc. 2015, 137, 11946-11949.
(News story describing this work was highlighted in Chem. & Eng. News 2015, 93, 35)
9. Dao, H. T.; Li, C.; Michaudel, Q.; Maxwell, B. D.; Baran, P. S.* “Hydromethylation of Unactivated Olefins”
J. Am. Chem. Soc. 2015, 137, 8046-8049.
8. Dong, T.#; Li, C.#; Wang, X.; Dian, L.; Zhang, X.; Li, L.; Chen, S.; Cao, R.; Li, L.; Huang, N.; He, S.;* Lei, X.* “Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine”
Nature Commun. 2015, 6, 6522.
(News story describing this work was highlighted in Chem. & Eng. News 2015, 15, 39)
7. Li, C.#; Dong, T.#; Li, Q.; Lei, X.* “Probing the Anticancer Mechanism of (−)-Ainsliatrimer A through Diverted Total Synthesis and Bioorthogonal Ligation”
Angew. Chem. Int. Ed. 2014, 53, 12111-12115.
6. Li, C.; Lei, X.* “Strategies toward the Biomimetic Syntheses of Oligomeric Sesquiterpenoids”
J. Org. Chem. 2014, 79, 3289-3295.
5. Li, C.; Dong, T.; Dian, L.; Zhang, W.; and Lei, X.* “Biomimetic Syntheses and Structural Elucidation of the Apoptosis-Inducing Sesquiterpenoid Trimers: (-)-Ainsliatrimers A and B”
Chem. Sci. 2013, 4, 1163-1167.
4. Li, C.; Li, X.; Wang, X.; Lei, X.* “Diversity-oriented Synthesis of Bicyclic Ring Systems via a Conjugate Addition/aldol/RCM Process”
Sci. China. Chem. 2013, 56, 337-341.
3. Li, C.; Dian, L.; Zhang, W.; Lei, X.* “Biomimetic Syntheses of (-)-Gochnatiolides A-C and (-)-Ainsliadimer B”
J. Am. Chem. Soc. 2012, 134, 12414-12417.
2. Li, C.; Tu, S.; Wen, S.; Li, S.; Chang, J.; Shao, F, Lei, X.* “Total Synthesis of the G2/M DNA Damage Checkpoint Inhibitor Psilostachyin C”
J. Org. Chem. 2011, 76, 3566-3570.
1. Li, C.; Yu, X.; Lei, X.* “A Biomimetic Total Synthesis of (+)-Ainsliadimer A”
Org. Lett. 2010, 12, 4284-4287.